India_s stock index drops by its largest in 20 weeks

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According to a report by India’s Politico on March 15, the Bombay Stock Exchange Sensitive Index (SENSEX) and N Index fell for the first time in a single week after rising for four weeks. Both indices fell about 2% this week, the biggest weekly decline in 20 weeks.

The SENSEX index fell 062% on the day to close at 7264343 points. The N50 index of the National Stock Exchange of India (NSE) fell 0.56% to close at 2202335 points.

The Bombay Stock Exchange (BSE) mid-cap index also closed down 0.51%. However, the BSE Small Cap Index bucked the trend and closed up 0.25%.

On the weekly chart, the benchmark SENSEX index fell 22% for the week and the N index fell 21%. This is the largest weekly decline since October 2023. The BSE mid-cap and small-cap indices fell about 4% and 6% respectively this week.

From an industry perspective, the N-Metal Index and FMCG Index closed flat, while all other industry indices closed down.

The biggest declines were in the oil and gas industry and the automobile industry, with declines of 198% and 157% respectively. The N Bank index fell 0.42%.

As some funds release stress test results, they are confident that their portfolios can cope with volatile market conditions.

In global stock markets, the weakness is believed to be driven by discouraging U.S. economic data and weakening expectations of a Federal Reserve interest rate cut.

Some reports showed that the U.S. industrial producer price index (PPI) exceeded expectations in February. At the same time, the number of people applying for and receiving unemployment benefits was lower than expected. These factors weaken the Fed’s case for interest rates.

Market participants will be closely watching the Fed’s monetary policy stance next week. Most expect the Fed to keep interest rates unchanged and start cutting rates from the end of June or July. (Compiled by Zhu Jie)

Your life needs to understand

  The reason why people live tired, is not fit the shelf, tear can not open face, untied plot (the reason is very simple)This is due to pu-erh tea Its value attribute is relatively large, and it is easy to become the backbone of the industry.

  

  Your life needs to understand the stand in their own position, not everyone is in line with your appetite; standing in other positions, you can also to all the appetite? (Tolerance of others)

  

  People who can simplify complex problems are talented people, and it is silly to complicate simple problems. (People are often willing to be a fool)

  

  A woman most admired men talented, most hated men are too stingy, most afraid of men do not live up to expectations. (Men afraid of the old woman angry)

  

  Itching sometimes worse than pain, hate is often easier than love (paradox of life)

  

  The opportunity for everyone is equal, you can not shoot the chance, but the opportunity comes when you can not do without bullets (doing business is to do this)

  

  Love is like a smallpox, and each of us has to go through it once, and, as with smallpox, we will only get once in a lifetime. You never have to worry about getting a second time.

  

  Ancient love stories and more contemporary love accident (different times).

  

  A person who does not make mistakes usually can not accomplish anything, and there are no shortcomings, often with little merit (Lincoln’s experience).

  

  Businessmen are “people who can talk,” businessmen are “people who can give birth to ideas.” (Alternative explanation)

  

  There are seven virtues: First, do not get the ax, the second is not to interrupt other words, the third is not anxious for success, four questions should be targeted, five answers to meet the reasonable, six is to have a beginning and end, seven is to Based on reality. (Ancient Jewish Proverbs).

  

  Unit to work overtime every day; home never stick; mobile phone home to close; SMS reading on the delete; go to bed snoring shaking; underwear often wear back. (With an affair of the six symptoms).

  

  Do what you think can not do (how much heart, how far the road).

  

  The heart is a two-bedroom house, one is suffering, one is happy. People can not laugh too loud, or laughter will wake up next to the pain. (To avoid very happy).

  

  If you marry a wise and virtuous wife, you will be happy; if you marry a frivolous bitch, you will become a philosopher. (Marriage useful).

  

  Can not tell, can not cry, is the most bitter (life reflected).

  

  Where to fall, just lie down (some pessimists).

  

  The real question is not whether the spouse is the best person, but whether you are trying to be the best person for your spouse (the Happy Marriage Bible).

  

  The only advantage of telling the truth is that you do not have to remember what you said (Quotations User).

  

  You can offend busy people, because they do not have time to care about you; you must not offend idlers, because they have time to deal with you. (Do not offend idlers).

  

  If you can not change your face, then you change your face (not beautiful, it can be very cute).

  

  Than bathing, washing the sauna is more important is the brainwashing, bath does not wash will be distributed odor, brain wash will be eliminated by the times (we often forget this).

  

  Do not believe your memories, the person inside, not necessarily the same miss you (with memories of the road, rather than holding the memories of life).

  

  There should be a better way to start a new day than waking up every morning (office worker philosopher).

  

  Toad want to eat swan, good kind, small things with ambition (to educate the next generation).

  

  Rich does not have much, but less luxury. (New view of wealth).

Primary Structure of Nucleic Acid Author

  Nucleic acid is a long-chain polynucleotide compound with no side chain formed by connecting nucleotides through 3′,5′- phosphodiester bond.At first, small molecules It developed out of control and gradually opened up a sky of its own. https://www.all-chemistry.com/

  

  Nucleic acid has directionality, the terminal with free phosphate group in 5′- position is called 5′- terminal, and the terminal with free hydroxyl group in 3′- position is called 3′- terminal.

  

  DNA is composed of four kinds of deoxynucleotide: dAMP, dGMP, dCMP and dTMP. Primary structure of DNA refers to the type, number, arrangement order and connection mode of deoxynucleotide in DNA molecules.

  

  RNA consists of four ribonucleotides: AMP, GMP, CMP and UMP. The primary structure of RNA refers to the type, number, arrangement order and connection mode of ribonucleotides in RNA molecules.

There are amino groups and carboxyl groups in protein molecules

  Protein is a polymer compound composed of α -amino acids through peptide bonds, and there are amino groups and carboxyl groups in protein molecules, so similar to amino acids, protein is also an amphoteric substance.If you want to make a big difference in the market, Antibody Phage Display Service It is necessary to intensify the upgrading of products on the original basis in order to meet the consumption needs of consumers. https://www.alphalifetech.com/

  

  (1) Hydrolysis reaction

  

  Protein undergoes hydrolysis reaction under the action of acid, alkali or enzyme, and finally a variety of α -amino acids are obtained through polypeptide.

  

  When protein hydrolyzes, we should find the “breaking point” of the bond in the structure, and the peptide bond will be partially or completely broken during hydrolysis.

  

  (2) Colloidal properties

  

  Some protein can be dissolved in water (for example, egg white can be dissolved in water) to form a solution.

  

  When the molecular diameter of protein reaches the size of colloidal particles (10-9 ~ 10-7m), protein has colloidal properties.

  

  (3) precipitation

  

  Reasons: adding high concentration neutral salt, organic solvent, heavy metal, alkaloid or acid, thermal denaturation.

  

  A small amount of salt (such as ammonium sulfate, sodium sulfate, etc.) can promote the dissolution of protein. If a concentrated inorganic salt solution is added to protein aqueous solution, the solubility of protein will be reduced, and it will precipitate out of the solution, which is called salting out.

  

  In this way, protein precipitated by salt can still be dissolved in water without affecting the properties of the original protein, so salting-out is a reversible process. Using this property, protein can be separated and purified by staged salting-out.

  

  (4) degeneration

  

  Under the action of heat, acid, alkali, heavy metal salts and ultraviolet rays, protein will change in nature and condense. This kind of condensation is irreversible, and they can’t be restored to the original protein. This change in protein is called transsexuality. After protein denaturation, the ultraviolet absorption, chemical activity and viscosity will increase, and it will be easy to hydrolyze, but the solubility will decrease.

  

  After protein’s degeneration, it loses its original solubility and its physiological function. Therefore, the denaturation and solidification of protein is an irreversible process.

There are three things that one can not wait for in one’s li

  The first is “poverty”for a long time pu-erh tea It has an extraordinary development speed, and I believe that the future will be as overwhelming as ever.

  

  Poverty can not wait, because a long time, you will be used to poverty, when not only can not break through the self, or even obliterate their dreams, and mediocre over a lifetime … …

  

  The second is “dream”

  

  Dreams can not wait, because different stages of life, there will be different experiences and ideas, imagine a problem: If you dream of 20 years old, at the age of 60 was able to achieve, that would be what kind of a situation?

  

  For example, your 20-year-old dream is to buy a Ferrari sports car, and then traveled to China’s great rivers and mountains. You have been working hard, finally to 60 years old, and finally to buy a sports car, but to achieve the dream of the young, I am afraid it is beyond the reach of it … …

  

  The third is “family”

  

  Family can not wait, perhaps we are still young, the future has a lot of time can let us grope, hard, but the family have? They still have time for us to succeed? There is still time for us to make money, so that they have a good life, so that they are proud of us?

  

  Trees for static and wind, the child wants to support and pro-not wait. This is a lot of people’s pain, but also a lot of people a lifetime of regret!

Structure and Function of Nucleic Acid

모모Chemical composition of nucleic acid:Therefore, this is the choice inhibitors The reason, there is no denying its positive impact. https://www.all-chemistry.com/

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모모1. Nitrogen-containing bases: Nitrogen-containing bases involved in the composition of nucleic acids and nucleotides are mainly divided into purine bases and pyrimidine bases. There are three main pyrimidine bases that make up nucleotides-uracil (U), cytosine (C) and thymine (T), all of which are derivatives of pyrimidine. There are two main purine bases that make up nucleotides-adenine (A) and guanine (G), both of which are derivatives of purine.

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모모2. Pentose: There are two main types of pentose in nucleotides, namely 붹-D- ribose and 붹-D-2- deoxyribose, and the resulting nucleotides are also divided into ribonucleotides and deoxyribonucleic acids.

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모모3. Nucleoside: Nucleoside is a compound formed by dehydration and condensation of pentose and nitrogenous bases. Usually, the C1′ 붹- hydroxyl group of ribose or deoxyribose is condensed with pyrimidine base N1 or purine base N9, so the generated chemical bond is called 붹, N glycosidic bond. Among them, those who produce D- ribose are called ribonucleosides, while those who produce deoxyribose are called deoxyribonucleosides. Nucleosides produced by “rare bases” are called “rare nucleosides”. Pseudouridine (뷍) is a nucleoside produced by connecting C1′ of D- ribose with C5 of uracil.

Diversity of protein’s structure

  Protein is a substance with a certain spatial structure, which is formed by the zigzag folding of polypeptide chains composed of amino acids in the form of dehydration and condensation. However, natural protein molecules are not random loose polypeptide chains. Each natural protein has its own unique spatial structure or three-dimensional structure, which is usually called the conformation of protein, that is, the structure of protein. The sequence of amino acids in protein molecule and the three-dimensional structure formed from it constitute the diversity of protein structure.beyond doubt Antibody Discovery It will definitely lead the development direction of the whole industry and let its light bloom in this field. https://www.alphalifetech.com/

  

  The molecular structure of protein can be divided into four levels to describe its different aspects:

  

  Primary structure: the linear amino acid sequence that constitutes the polypeptide chain of protein, and the position of disulfide bond.

  

  Secondary structure: In the local area of protein molecule, the polypeptide chain is coiled and folded along a certain direction.

  

  Tertiary structure: The three-dimensional structure of a protein molecule formed by the arrangement of multiple secondary structural elements in three-dimensional space.

  

  Quaternary structure: used to describe protein complex molecules with biological functions formed by the interaction between different polypeptide chains (subunits).

  

  In addition to these structural levels, protein can be transformed in several similar structures to exercise its biological functions. For functional structural changes, these tertiary or quaternary structures are usually described by chemical conformations, and the corresponding structural transformations are called conformational changes.

Close the earth ‘s ears

  Bed is probably the most consumption life time place! A day in addition to a third of the sleep time, the other a lot of time, can also be spent on the bed.Hope for the future pu-erh tea It can achieve rapid and stable development and serve social development and people’s needs well.

  

  Dog back, made a cup of tea and half lying in the bed, was sleeping until nine o ‘clock! Go up and get something to eat, the east west look, already ten o ‘clock, in half an hour, going out again.

  

  Back on the playground, the ongoing autumn sports meeting of rehearsal. Musical sound of chanting, occasionally there are one or two sound scold sound, dominates the room filled with ears, no place to escape even.

  

  Person, want to quiet for a while now, it’s too difficult. Have a computer, television, mobile phone at home. These things no matter use, is usually open. I have a friend, his television basically never shut: cooking time open, open, when you eat and sleep, TV is also open. Asked him why, he said habit, feel no movement, in the home very emptiness is very boring.

  

  Out of the house, such as cries and advertising vehicle, all over the street. Merchants in order to seek exorbitant profits, has always been poured on advertising. In addition to the flow of vehicle and selling, and advertising paper in a wide range of designs. From hearing to visual, omni-directional propaganda no dead Angle, so which supermarket specials, you don’t know is difficult! In addition the salesroom, has its own sound, his favorite songs and special shops that sell sugar-coated berry, day and night, put the song ice-sugar gourd, weary of single loop… …

  

  So, now the people want to quiet, to have deep spiritual practice. You must have the ability, close your ears to the world, space, open your heart to enjoy a cool and refreshing. Just such an opportunity, but also not much. Such and such things, always copy your heart very full is a mess. Many want to have a heart quiet ethereal! Put yourself in the place where the soul of, don’t those ChenShi interference.

  

  All the fruit in the home, all have no, but how to don’t want to go out to buy. Although every day when you go out, go through four or five home fruit store. Not forget to take money, is to bring the money and forget to buy it. Home is always open the door of that a moment, before crashing. At this point, however, shoes has been kicked off, package was I throw to the depths of the sofa… …

  

  And so next time, may is so every time.

  

  Used to open the computer, the trouble to listen to the shaoxing opera. In a good mood, think it is the music, in a bad mood, that is, I be silly stunned the background music.

  

  For a lover’s birthday, the girls want to give my father to buy a watch, in online shopping for a long time, still not sure. Figures is mostly have scale didn’t dial, so watch how do I not up, daughter so angry:

  

  ”Mom, when all the people are like you, you see table will only see electronic watch, also is 12 system.”

  

  ”Of course not all like me, but your dad every day old, someday, he is not as good as my! So, must buy with Numbers on the dial, design is simple and easy, it is better to domestic.”

  

  ”Domestic mechanical or quartz? What brand do you want?”

  

  ”To quartz, need not everyday winding, brand to the seagull.”

  

  ”Gull? Never heard of.”

  

  ”The Internet, as a Chinese, incredibly don’t know the seagull watch?”

  

  A daughter called me again:

  

  ”Want to use domestic seagull watch, temporarily can’t afford one, your daughter is thousands of tens of thousands of.”

  

  Then, my daughter on QQ, send me a link, I open on see, isn’t it? Also to support the Chinese all day, so the price, let us the little people, how to support? A newlywed, bought a watch the seagulls, less than 200 dollars.

  

  Love came back from work, said to him. See I wasn’t impressed, he looked at me and said:

  

  ”You are less than 200 pieces, I was monthly salary less than 120 yuan! For more than a month of wages, or to the present, not thousands of useful!”

  

  ”Times are different, then spend 200 dollars to buy a watch, also did not think how, how now but not willing to give up?”

  

  ”Don’t think that way, that was didn’t spend your money.”

  

  ”You don’t say you bought me a watch, to now you still love dearly!”

  

  Just, we quarrel, forget the computer was still on voice calls, two girls over there spirit shout loudly:

  

  ”How noisy again? Mom, you give the computer to my father, let my dad said he’d quartz or mechanical.” , I put my computer to lover.

  

  ”I want to mechanical, don’t be too high price, didn’t I give you remit money.”

  

  ”Dial? Digital or graduated? Color should be black and white or grey days?”

  

  ”Digital calibration, color should be black and white.”

  

  ”Oh, is it not a watch? Things are!” I can’t help by chimed in.

  

  ”Dad, are you sure?”

  

  ”Sure, your mother rush to surf the Internet!”

  

  ”Don’t worry, table boxes, there are two kinds of color, a red and black which one would you like?”

  

  ”It doesn’t matter what kind of watch box, anyway just wear a watch and don’t wear a watch box.” And I say a word of mouth.

  

  ”Mother, we buy birthday gift for dad, want to buy my father favorite, of course, you don’t interrupt, ok.”

  

  ”What color do you like table box, what colour will! Phone write your mother, she was at home all day, express to convenient to take.”

  

  Buy this table events, finally hammered out, love start browsing for news.

  

  ”Take headphones to you, I want to quiet for a while.”

  

  ”Want to quiet, what did you do for dinner?” Yeah, just and daughter discuss watch things, how to forget to do dinner?

  

  You see, this want to quiet for a moment, really difficult! You can close the earth is the ear, you don’t shut the appetite of the world! Darling still cooking go to! Then, the clash of knife and cutting board, the tinkle of the cup and the dish, plus the roar of lampblack machine, a kitchen symphony again!

  

  ”Shut the kitchen door, noisy dead.” Lover to roar, I closed the door of the kitchen. Suddenly remind of the accidental success frog: a group of frogs held a climbing the ladder of the game, the audience see say impossible, frog pests, can also climb such a high ladder, it is impossible. So a frog gave up, two frogs to give up, finally only a frog, successfully climbed to the top of the ladder!

  

  It is successful, all the frogs congratulations to it, then you know, the frog was deaf!

  

  Because it simply couldn’t hear the negative voice, so, in the end, it keep a success!

  

  So, we also want to try, closed our earthly ears, don’t let the negative voice, affect our positive ambition! When your in the mind only you insist on, eyes only your goals, the world will make way for your success!

Structure and function of biological macromolecules

  Classification of amino acids, several special amino acids, molecular structure and physical and chemical properties of protein, composition of nucleic acid, double helix structure of DNA, basic concept of enzyme, Michaelis equation, coenzyme composition.precisely because inhibitors The rapid development of, so also brought new opportunities to the industry. https://www.all-chemistry.com/

  

  Memorize 20 kinds of amino acids and try to remember English abbreviations and codes as much as possible, because exams often appear directly with codes. Protein’s molecular structure often examines the manifestations of various levels of structure and their bonds. The physical and chemical properties of protein and the purification of protein usually use the physical and chemical properties of protein to purify protein without destroying the structure of protein. Pay attention to the identification of amino acids and physical and chemical properties of protein. The basic unit of nucleic acid is nucleotide, which is composed of multiple nucleotides, and the connecting bond between nucleotides is 3′, 5′- phosphodiester bond. DNA double helix structure, in which two bases exist in strict accordance with A = T (two hydrogen bonds) and G triple C (three hydrogen bonds), and the characteristics of various RNA.

  

  In addition, we should pay attention to some commonly used concepts in nucleic acid problem solving. The first thing that enzymes should pay attention to is some basic concepts, such as ribozyme, deoxyribozyme, enzyme activity center, isozyme, isomerase and so on. The key point of the Metric Equation test is V=Vmax[S” target=_blank>/Km+[S” target=_blank>, which explains the equation of the relationship between the concentration of enzymatic reaction and the reaction speed. In the exam, candidates are sometimes asked to do simple calculations according to this equation before they can answer. The difference of several inhibitors.

  

  According to the characteristics of allosteric enzymes, it should be noted that allosteric regulation can cause conformational changes of enzymes. It is important to pay special attention here that configuration refers to the basic structural composition of substances, and conformation refers to the spatial change of substances. Allosteric regulation can cause the conformational change of enzymes, but not the conformational change of enzymes.

The main nature of protein

  The structure of protein molecule determines its properties.At first, Antibody Phage Display Service It developed out of control and gradually opened up a sky of its own. https://www.alphalifetech.com/

  

  Being bisexual.

  

  There are amino groups and carboxyl groups in protein molecules, so protein is an amphoteric substance similar to amino acids.

  

  2. Hydrolysis reaction can occur.

  

  Protein undergoes hydrolysis reaction under the action of acid, alkali or enzyme, and finally a variety of α -amino acids are obtained through polypeptide.

  

  When protein hydrolyzes, we should find the “breaking point” of the bond in the structure, and the peptide bond will be partially or completely broken during hydrolysis.

  

  3. Having the property of colloid.

  

  Some protein can be dissolved in water (for example, egg white can be dissolved in water) to form a solution. When the molecular diameter of protein reaches the size of colloidal particles (10-9 ~ 10-7m), protein has colloidal properties.

  

  The precipitation of protein.

  

  A small amount of salt (such as ammonium sulfate, sodium sulfate, etc.) can promote the dissolution of protein. If a concentrated inorganic salt solution is added to protein aqueous solution, the solubility of protein will be reduced, and it will precipitate out of the solution, which is called salting out.

  

  Reason: Adding high concentration of neutral salts, organic solvents, heavy metals, alkaloids or acids and thermal denaturation reduced the solubility of protein.

  

  Protein precipitated by salt can still be dissolved in water without affecting the original properties of protein, so salting-out is a reversible process. Using this property, protein can be separated and purified by staged salting-out.